{
  "schemaVersion": 1,
  "slug": "open-targets",
  "name": "open-targets",
  "description": "Ask the Open Targets Platform what is already known about a target or a disease — scored target-disease associations, the individual evidence records behind each score with their source and publication, tractability, and clinical candidates — over a public GraphQL API with no account. Resolves gene symbols and disease names to the Ensembl and MONDO identifiers the API demands.",
  "category": "data",
  "version": "1.0.0",
  "author": "Heureka Labs",
  "license": "CC-BY-4.0",
  "tags": [
    "open-targets",
    "drug-discovery",
    "human-genetics",
    "gwas",
    "public-data"
  ],
  "covers": [
    "open targets",
    "target identification",
    "target validation",
    "therapeutic target",
    "druggability",
    "tractability",
    "gene disease association",
    "target-disease association",
    "association score",
    "evidence",
    "provenance",
    "known drugs",
    "clinical trial phase",
    "chembl",
    "gwas",
    "somatic mutation",
    "cancer driver",
    "clinvar",
    "orphanet",
    "rare disease",
    "mouse model",
    "text mining",
    "europe pmc",
    "mondo",
    "efo",
    "disease ontology",
    "graphql",
    "tp53",
    "egfr",
    "breast carcinoma"
  ],
  "papers": [
    "PMID:27899665",
    "PMID:30462303",
    "PMID:33196847",
    "PMID:36399499",
    "PMID:39657122"
  ],
  "access": [
    "open"
  ],
  "platform": "opentargets",
  "updatedAt": "2026-08-27T10:29:48-04:00",
  "source": {
    "repo": "heurekalabsco/heurekaskills",
    "commit": "39b38602c74abeb725438a3906d881fcba5f3cd6",
    "path": "skills/open-targets"
  },
  "checksum": "sha256:fe198ff61b97e6759dea7d870a08309147edda8219b68ec38415df11370a3d59",
  "signals": null,
  "files": [
    {
      "path": "SKILL.md",
      "url": "https://heurekaskills.com/open-targets/files/SKILL.md",
      "size": 63739,
      "sha256": "b738e593f80532975db4abcd3d46695a9118f5fdfbbea97607421b3213a50d92"
    }
  ]
}