{
  "schemaVersion": 1,
  "slug": "bindingdb",
  "name": "bindingdb",
  "description": "BindingDB measured protein–ligand affinities (Ki, IC50, Kd, EC50) — query by UniProt or compound, stream one target's set from the monthly TSV with each row's licence, keep > and < values as bounds, and avoid double counting with ChEMBL.",
  "category": "data",
  "version": "1.0.0",
  "author": "Heureka Labs",
  "license": "CC-BY-4.0",
  "tags": [
    "public-data",
    "drug-discovery",
    "cheminformatics",
    "binding-affinity"
  ],
  "covers": [
    "bindingdb",
    "binding affinity",
    "protein-ligand",
    "ki",
    "ic50",
    "kd",
    "ec50",
    "pki",
    "pic50",
    "inhibitor",
    "small molecule",
    "ligand",
    "target",
    "uniprot",
    "us patent",
    "medicinal chemistry",
    "sar",
    "structure-activity relationship",
    "qsar",
    "training data",
    "drug discovery",
    "kinase",
    "enzyme inhibition",
    "censored values",
    "chembl overlap",
    "ucsd",
    "egfr",
    "nik",
    "map3k14",
    "imatinib"
  ],
  "papers": [
    "PMID:39574417",
    "PMID:26481362"
  ],
  "access": [
    "open"
  ],
  "updatedAt": "2026-10-23T07:34:08-04:00",
  "source": {
    "repo": "heurekalabsco/heurekaskills",
    "commit": "c03b67d93fcbaba270dda38427ac267dd75ec120",
    "path": "skills/bindingdb"
  },
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  "signals": null,
  "files": [
    {
      "path": "SKILL.md",
      "url": "https://heurekaskills.com/bindingdb/files/SKILL.md",
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}