{
  "schemaVersion": 1,
  "slug": "antifold",
  "name": "antifold",
  "description": "Design antibody and nanobody CDR sequences on a fixed Fv backbone with AntiFold — per-residue log probabilities, region and IMGT-position constraints, CPU inference. Covers the renamed output columns and how a non-Fv chain still scores.",
  "category": "models",
  "version": "1.0.0",
  "author": "Heureka Labs",
  "license": "CC-BY-4.0",
  "tags": [
    "antibody-design",
    "inverse-folding",
    "nanobody",
    "antifold"
  ],
  "covers": [
    "antibody",
    "nanobody",
    "VHH",
    "Fab",
    "Fv",
    "CDR",
    "CDRH3",
    "framework",
    "IMGT numbering",
    "inverse folding",
    "sequence design",
    "humanisation",
    "affinity maturation",
    "library design",
    "ESM-IF1",
    "SAbDab",
    "OAS",
    "antibody engineering",
    "variable domain"
  ],
  "updatedAt": "2026-10-20T08:47:02-04:00",
  "source": {
    "repo": "heurekalabsco/heurekaskills",
    "commit": "87bef344c860de2523de46617b1f9e4d0a34c5ac",
    "path": "skills/antifold"
  },
  "checksum": "sha256:c48c52bee6048e1e6dadca9ddbae504e38613f028bb11344dc3cd88ea5673574",
  "signals": null,
  "files": [
    {
      "path": "SKILL.md",
      "url": "https://heurekaskills.com/antifold/files/SKILL.md",
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}