{
  "schemaVersion": 1,
  "slug": "4dn",
  "name": "4dn",
  "description": "Search and download 4D Nucleome chromatin architecture data — in situ Hi-C, Micro-C, HiChIP, ChIA-PET, SPRITE, DamID, Repli-seq, ATAC-seq and imaging (DNA FISH, single particle tracking) across human and mouse cell lines and tissue. Walks ExperimentSet to Experiment to File, checks each file's access tier before transferring, and pulls open files from the AWS Open Data bucket with no account.",
  "category": "data",
  "version": "1.0.0",
  "author": "Heureka Labs",
  "license": "CC-BY-4.0",
  "tags": [
    "4dn",
    "hi-c",
    "chromatin",
    "public-data",
    "controlled-access"
  ],
  "covers": [
    "4d nucleome",
    "in situ hi-c",
    "micro-c",
    "capture hi-c",
    "hichip",
    "chia-pet",
    "sprite",
    "damid",
    "tsa-seq",
    "repli-seq",
    "atac-seq",
    "chip-seq",
    "rna-seq",
    "dna fish",
    "multiplexed fish",
    "single particle tracking",
    "chromatin architecture",
    "chromosome conformation",
    "topologically associating domain",
    "chromatin loops",
    "a/b compartments",
    "insulation score",
    "contact matrix",
    "mcool",
    "cooler",
    "h1-hesc",
    "gm12878",
    "hffc6",
    "human",
    "mouse"
  ],
  "papers": [
    "PMID:28905911",
    "PMID:35501320",
    "PMID:32213324",
    "PMID:34480151",
    "PMID:37845234"
  ],
  "access": [
    "open",
    "registered",
    "controlled"
  ],
  "platform": "snovault",
  "updatedAt": "2026-08-27T10:37:08-04:00",
  "source": {
    "repo": "heurekalabsco/heurekaskills",
    "commit": "39b38602c74abeb725438a3906d881fcba5f3cd6",
    "path": "skills/4dn"
  },
  "checksum": "sha256:9dcbc4930e73f0174539e801ef3c3b9d25f315e4a7484e060488a3bc6c5fba3e",
  "signals": null,
  "files": [
    {
      "path": "SKILL.md",
      "url": "https://heurekaskills.com/4dn/files/SKILL.md",
      "size": 53540,
      "sha256": "82dcceb95c9346247c3f92abf76f81872688ca2432e9ea93cb23c6fb9f524589"
    }
  ]
}